In many ways, Proviron is a very unique anabolic steroid. It shares some strong similarities to Masteron (Drostanolone) and to a degree Anavar (Oxandrolone) and Winstrol (Stanozolol) but in totality, it is its own unique animal. In a performance capacity, Proviron is not used to promote large buildups in mass, although it can serve an important purpose during such a phase of training. We will, however, find Proviron to be far more common in cutting cycles, but once again its purpose will be somewhat unique.
As a therapeutic agent, Proviron is one of the most commonly used anabolic steroids in modern medicine. However, the Mesterolone hormone has never been approved by the U.S. FDA. It will primarily be found in European medicine, especially in Western Europe. The primary purpose of use is treating androgen deficiencies, age being the most common culprit of the condition. It is, however, also used in pre-pubescent males as well. The hormone is also used as a fertility aid in men and this alone makes it a very unique anabolic steroid as most anabolic steroids tend to have the opposite effect.
Proviron Functions & Traits:
Proviron carries an androgenic rating of 30-40 and an anabolic rating of 100-150. All ratings derive from and are measured against testosterone, which carries a rating of 100 in both categories. Despite having an anabolic rating that is potentially greater than testosterone, Proviron will display very low anabolic traits. This is very similar to Halotestin (Fluoxymesterone), which carries a massive anabolic rating but very little translatable anabolic activity. In the case of Proviron, while structurally very anabolic, the Mesterolone hormone converts and reduces to Diol metabolites, in turn reducing anabolic activity.
However, Proviron’s androgenic rating is a different story. In fact, its translatable androgenic activity appears to commonly be higher than its structural rating would imply.
On a functional basis, Proviron carries four primary traits that largely define its mode of action. First and foremost the Mesterolone hormone has a strong binding affinity to Sex-Hormone-Binding-Globulin (SHBG). In fact, it appears to be one of the strongest anabolic steroids in this regard.
Proviron also has the ability to interact with the aromatase enzyme, the enzyme responsible for the conversion of testosterone to estrogen. By binding to the aromatase enzyme, Proviron can actually inhibit aromatase activity, thereby offering protection against estrogenic side effects.
The Mesterolone hormone will also carry a strong binding affinity to the androgen receptor. Once again this will promote the functionality of other steroids to a degree but more importantly promote enhanced metabolic activity through direct lipolysis. This not only enhances the amount of sperm produced but greatly and equally important enhances the quality of the sperm.
Side Effects of Proviron:
There are possible side effects of Proviron use; however, this steroid carries one of the highest safety ratings among all anabolic steroids. Most men will be able to use this steroid without any negative issue, but possible side effects do exist despite a low probability. When it comes to female use, in a therapeutic or performance capacity this steroid cannot be recommended. The rate of virilization is much too high and should be avoided by females who wish to protect their femininity.
The Mesterolone hormone is not estrogenic. It does not aromatize and it carries no progestin nature. As a result, the side effects of Proviron will not include any related effects such as gynecomastia or excess water retention. Such adverse effects are impossible with this steroid. This will also greatly reduce the risk of high blood pressure as hi gh blood pressure associated with anabolic steroid use is often due to extreme water retention. In fact, Proviron should provide an anti-estrogenic effect by preventing testosterone to estrogen conversion or at least tremendously slow it down.
Such side effects of Proviron can include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. Such effects are highly dependent on genetic predispositions. For example, those who are not genetically prone to male pattern baldness will not lose any hair. Those who are not sensitive to acne should not have any issues with breakouts.
Due to the potent androgenicity of Proviron, it will lead to severe virilization in women. This can and will more than likely include body hair growth, a deepening of the vocal cords and clitoral enlargement.
Cardiovascular strain, particularly cholesterol issues will be the most concerning side effect of Proviron. This anabolic steroid can negatively affect cholesterol at a far more pronounced rate than most anabolic steroids. If you suffer from high cholesterol you should not touch this steroid.
The Mesterolone hormone has the ability to greatly affect HDL and LDL cholesterol. It is very possible to use Proviron without harsh cholesterol issues becoming a concern, but it will take some effort.
Due to minimal testosterone suppression, it is possible to use this anabolic steroid without exogenous testosterone or at least with a very minimal amount. An individual could implement a cycle of Anavar along with Proviron and keep his testosterone levels from falling to a very low range. However, most will be using other anabolic steroids that are highly suppressive to natural testosterone production along with Proviron making the use of exogenous testosterone imperative. Those who do not include it will put their body into a low testosterone state. Such a state can come with numerous bothersome symptoms and is extremely unhealthy.
Despite being an oral anabolic steroid, Proviron is not hepatotoxic. This is not a C17-aa anabolic steroid and will not burden the liver with any stress or damage.
Standard Proviron doses to treat androgen or male fertility will normally fall in the 50-75mg per day range. Normally the total dosing is split into 2-3 25mg doses per day. In androgen deficiency plans, the total dosing almost always starts at 75mg per day and slowly reduces to 25-50mg per day depending on patient need.
In a performance capacity, Proviron doses normally range from 50-150mg per day. Most men, however, will find 100mg per day to be the minimum beneficial dose with both 100mg and 150mg being highly effective. Total use will normally last between 8-12 weeks. However, in an effort to break through a sticking point in a cycle, say towards the end of a cycle a 6-week course of Proviron may do the trick.